The fact that the chemical Bisphenol A, which is in many plastic bottles and packaging, so that they remain supple, could be harmful to health, has already been expressed by various research institutes. In 2011, the European Commission banned baby bottles.

Studies indicate that the substance, or BPA for short, could be associated with cardiovascular disease, breast and prostate cancer and neuronal diseases. The use of BPA in plastic food packaging should therefore be limited, researchers suggest. The Federal Institute for Risk Assessment (BfR), the European Food Safety Authority (Efsa), the US Food and Drug Administration (FDA), the US National Institutes of Health (NIH) and the American Breast Cancer Foundation have already critically evaluated BPA.

Now results of another study point in this direction. Bisphenol A interferes with the function of proteins that are crucial for growth processes in cells. This is reported by researchers from the Ruhr University Bochum and the Bergische Universität Wuppertal. So far, it has been thought that BPA binds to hormone receptors and thereby unfolds its harmful effects.

Bisphenol A works in the body like the female hormone estrogen


The team of chemists and biochemists discovered that the substance also acts on the so-called small GTPases, the Ruhr-Universität announces. Small GTPases are enzymes that can exist in two states in the cell. The switch proteins are crucial for relaying signals in the cell. “Our study provides further evidence that the physiological effects of bisphenol A appear to be even more complex than previously thought,” says Prof. Raphael Stoll, head of the Biomolecular Spectroscopy Group of the Ruhr University.